Research

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CCHE’s location within the University of Chicago allows us to move smoothly between research, public health, community intervention, and clinical practice. We combine research and service in one location which allows for efficient bidirectional translation. Research directly informs our practice and our practice informs the research. Our current research focuses on highly at-risk groups in the Chicago area, especially younger black men who have sex with men (YMSM). The projects explore the ways that social networks influence HIV transmission patterns, how social support can affect an individual’s HIV care, and how networks can be leveraged for transformative intervention.

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Our Research

CCHE’s location within the University of Chicago allows us to move smoothly between research, public health, community intervention, and clinical practice. We combine research and service in one location which allows for efficient bidirectional translation.  Research directly informs our practice and our practice informs the research. Our current research focuses on highly at-risk groups in the Chicago area, especially younger black men who have sex men (YMSM). The projects explore the ways that social networks influence HIV transmission patterns, how social support can affect an individual’s HIV care, and how networks can be leveraged for transformative intervention.  

C3 (RECRUITING)

The C3 project, Community network-driven COVID-19 testing of vulnerable populations in the Central US, aims to implement and evaluate a COVID-19 testing approach that combines an evidence-based Social Network Testing Strategy with community developed COVID-19 public health messages. C3 engages with disenfranchised people in COVID-19 testing and vaccination through social network referral combined with theory-driven COVID-19 prevention messaging. Eligible CJI and Latinx clients (and the overlap between the two) in states across the Central US TX, LA, AR, IN, IL are invited to enroll.

 

For more information contact Jeannette Webb at Jwebb9@medicine.bsd.uchicago.edu .

JPrEP (RECRUITING)

The goal of this study is to determine awareness, acceptability, and early adoption of PrEP among jail-involved BMSM and BTW in the Chicago and Baton Rouge area through a one time in depth interview. Another goal is to examine awareness, acceptability, and feasibility of implementing PrEP within jail settings from the perspective of jail-involved stakeholders in the Chicago and Baton Rouge area through focus groups.

For more information, please contact MicKayla Jones at mxjones@medcine.bsd.uchicago.edu.

LINK2 (RECRUITING)

The purpose of this study is to assess outcomes of a novel intervention aiming to improve retention in care, ART adherence, and viral suppression among youth and young adults (ages 16-25) living with HIV who are involved with the criminal-justice system. All participants will complete 3 interviews/surveys over the course of 1 year. If placed in the intervention group participants will receive a navigator that will assist them with their HIV care for 6 months.

 

For more information, please contact Keyira Jones at kjones52@medicine.bsd.uchicago.edu.

N2 (RECRUITING)

The study, entitled “PrEP Uptake and Adherence Among Young Black MSM: Neighborhood and Network Determinants” is a behavioral study. The study goals and aims and other study-related information are described in detailed below.

Study Goals

The Specific Aims for this project are:

Specific Aim 1: Determine the relationship between neighborhood-level factors based on GPS-defined activity space neighborhoods (e.g. poverty, HIV prevalence and access to healthcare services, our primary predictors) and pre-exposure prophylaxis (PrEP) uptake and adherence

Specific Aim 2: Characterize the relationship between social and sexual network characteristics (e.g. network size, frequency of communication with network members, and material support, our primary predictors) and pre-exposure prophylaxis (PrEP) uptake and adherence

Specific Aim 3: Identify interactive effects of neighborhoods and social and sexual networks on pre-exposure prophylaxis (PrEP) uptake and adherence

 

For more information, please contact Hilary Hanson at hansonhd@uchicago.edu

PAC (RECRUITING)

The long-term goal of the Prevent Anal Cancer (PAC) Palpation Study is to decrease morbidity and mortality from anal cancer by increasing detection of anal canal tumors through self- or partner-palpation of the anal canal.

 

For more information contact Dejuan Washington at Dejuanw@medicine.bsd.uchicago.edu

W2P COVID Supplement

Work2Prevent aimed to advance the science by adapting, tailoring, and pilot-testing a novel social and structural-level HIV intervention for YMSM and YTW of color ages 16-24 aimed at increasing economic stability (i.e.,employment) through youth empowerment and asset development, and decreasing HIV risk behaviors(i.e.,sexwork) associated with social and economic marginalization. The COVID supplement will assess the impact of COVID on employment after 1 year of the COVID-19 pandemic. Study outcomes include: (1) job seeking self-efficacy and readiness; (2) employment; and (3) COVID-related attitudes and beliefs.

 

For more information please contact MicKayla Jones at mxjones@medicine.bsd.uchicago.edu

R03

This study aims to qualitatively identify common factors in cisgender women newly diagnosed with HIV and missed opportunities prior to diagnosis in those same women for PrEP linkage.

Aim 1: Identify commonalities among women with recent HIV diagnoses.

Aim 1a: Qualitatively assess common factors among women recently diagnosed with HIV (n=30) about potential intervention points and missed opportunities for PrEP linkage.

Aim 1b: Evaluate existing quantitative data sources (EMR, open source) for common factors among women with recent HIV diagnoses.

Aim 2: Develop an implementation plan for utilization of the refined automated identification of HIV-negative, PrEP-eligible women in the ED.

 

For more information, please contact Sam Devlin at sdevlin1@bsd.uchicago.edu

LAI-ART

Long-acting injectable antiretroviral therapy study addresses the need to identify LAI-ART implementation strategies across patient, provider, and clinic/systems contexts using a mixed-methods, multi-level study structured by the Consolidated Framework for Implementation Research (CFIR) with the goal of creating a care delivery model that optimizes real world use.

 

For more information please contact Rey Flores at reyflores@medicine.bsd.uchicago.edu 

ITM

This study aims to qualitatively identify common factors in cisgender women newly diagnosed with HIV and missed opportunities prior to diagnosis in those same women for PrEP linkage.

Aim 1: Identify commonalities among women with recent HIV diagnoses.

Aim 1a: Qualitatively assess common factors among women recently diagnosed with HIV (n=30) about potential intervention points and missed opportunities for PrEP linkage.

Aim 1b: Evaluate existing quantitative data sources (EMR, open source) for common factors among women with recent HIV diagnoses.

Aim 2: Develop an implementation plan for utilization of the refined automated identification of HIV-negative, PrEP-eligible women in the ED.

 

For more information, please contact Sam Devlin at sdevlin1@bsd.uchicago.edu

ETHIC

The goals of ‘Ending transmission of HIV, HCV, and STDs and overdose in rural

communities of people who inject drugs’ (ETHIC) are to:

 

  1. Determine the geographic areas in the rural Illinois Delta Region at greatest risk for opioid misuse and infectious diseases in the IDR based on disease surveillance, healthcare utilization, prescription drug monitoring, arrest and drug seizure, and resource scarcity using epidemiological analysis and GIS hot-spot mapping.
  2. Understand how sociocultural factors impact risk and health-seeking behaviors, social networks, and disease transmission of people who inject drugs in the IDR.
  3. Integrate and apply the epidemiological, geospatial, qualitative and network data to inform expanded harm-reduction services and targeted telehealth capacity building for related clinical care.
  4. Expand harm reduction services (HRS) including syringe services, naloxone overdose prevention, substance use treatment referral, HIV, HCV, and STD testing and referral and linkage to care through capacity building of existing programs.

 

For more information please contact Christian Johnson at cjohnson5@medicine.bsd.uchicago.edu .

P2M

The Phylodynamics-targeted Partner service Models (P2M) project aims to guide and transform the rapidly evolving public health implementation of molecular HIV surveillance (MHS) based prevention interventions as a critical step towards HIV elimination. P2M will expand an established partnership between a trans-disciplinary academic team and local health departments to evaluate next generation public health approaches that will more effectively target combination prevention to limit endemic spread of HIV and prevent future outbreaks. 

 

For more information please contact Rey Flores at reyflores@medicine.bsd.uchicago.edu 

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